: It uses basecalling models (like those from Guppy or Remora) to identify modified bases (e.g., 5mC, 6mA) and sequence variants directly from raw signal files. Key Features Modified Base Detection
: Ion Torrent uses semiconductor technology to detect hydrogen ions released during DNA polymerization, rather than measuring electrical current through a nanopore. Compatibility
: Capable of detecting epigenetic markers like 5mC CpG methylation. Mapping & Variant Calling
: It uses basecalling models (like those from Guppy or Remora) to identify modified bases (e.g., 5mC, 6mA) and sequence variants directly from raw signal files. Key Features Modified Base Detection
: Ion Torrent uses semiconductor technology to detect hydrogen ions released during DNA polymerization, rather than measuring electrical current through a nanopore. Compatibility
: Capable of detecting epigenetic markers like 5mC CpG methylation. Mapping & Variant Calling
